Dr.Herazy,

I have started using the medium plan.   I noticed, however, from your response to a question about Neprinol that you thought that Neprinol was more focused than Fibrozym and Nattokinase.  If this is so, why isn’t Neprinol included in the medium plan?

Thank you for your response.

Greetings,

There always seems to be some question about Neprinol when used in Peyronie’s treatment .   Here is something that I copied from the PDI website that you might have missed along the way that will explain my thinking about Neprinol in the initial plan usage:

“Hey, wait a minute!  I do not see NEPRINOL in any of these plans!  Why do you have Fibrozym and Nattokinase 1500 in these plans and not Neprinol?”   

“Neprinol is not included in the PDI Small, Medium or Large Plans for two reasons:

     “1.  Neprinol is more powerful than Fibrozym and Nattokinase 1500.  It contains the same enzymes as Fibrozym and Nattokinase 1500 – at perhaps 10-12 times greater bioactive activity.  It also contains different kinds of enzymes that are not found in Fibrozym and Nattokinase 1500.  So, Neprinol is more concentrated and has a greater variety of enzymes than these other products.  Therefore, based on my experience since 2002 with men who are treating their Peyronie’s bent penis, we have learned it is better to start treatment with the less intense and concentrated enzymes of Fibrozym and Nattokinase 1500 to get accustomed to the action of these enzymes; it is easier on the body and men have less diarrhea this way.   When you re-order the 1st or 2nd time you can then slowly introduce Neprinol into your treatment plan.

     “2.  Cost.  Because the bottle of Neprinol contains 300 capsules of more powerful and concentrated enzymes, as compared to 100 capsules in the other products, Neprinol costs more.  Therefore, after almost seven years experience working with men who are treating their Peyronies disease, we have found that men feel more comfortable keeping costs down when getting started.  The first order is the most expensive, and this is appreciated by men just starting who want to see how the suggested PDI plans work.”

I will usually suggest to men that after being on your plan for a few weeks or few months, or whenever you are comfortable adding Neprinol to your plan, that you do so.  Many men will later use Neprinol as the primary source of systemic enzymes in their plan, but also keep a few Nattokinase 1500 and Fibrozym in their plans as secondary or minor sources of systemic enzymes. 

When I was actively treating my Peyronies I took all three products, but with a greater emphasis on the Neprinol.  I do not think you must necessarily do it this way for you to be successful; I did it just to cover my bases and to keep my tissue as saturated as possible with the enzymes.

Peyronie’s disease is a tough and terrible thing to happen to a man.  It takes dedication and persistence to overcome it.   It is never easy to overcome, but always worthwhile.  

The biggest advantage in ordering your therapy products from PDI is that we provide a high level of service and background information specific to the problem of PD that you will not receive from anyone else.   Each product you order from PDI comes with all the information you will need to you it correctly to treat your Peyronie’s disease. You cannot expect that kind of vital information from any other source.   TRH

Hello Doctor,

I wish to know that is there any institute located in India which gives treatment for Peyronie.

With regards,
Rajan

Greetings Rajan,

I am not aware of any formal group or effort in India to treat Peyronie’s disease. 

The Peyronie’s Disease Institute is the only online effort to educate, treat and research this problem.   You can read and learn about Peyronie’s disease treatment online and in the two books I have written and undergo an active self-directed treatment plan based on the information and ideas found on this website.   If you have questions or concerns during the course of your treatment you are able to write me emails so I can share with you my experience and suggestions for help.   Usually men are very pleased and satisfied with this arrangement since they have come to learn that their own effort and interest is far better than what they receive from the average medical institution.  TRH

Dr. H – how does one gauge the presence/size of the plaque on the dorsal side of the penis ? Frankly, I do have the curvature but am not able to “feel?” the area that has been compromised.  Thanks

Greetings,

Location of the Peyronie’s plaque or scar is essential for effective and efficient Peyronies treatment.  For this reason an entire chapter was devoted in my first book, “Peyronie’s Disease Handbook” to help men locate and know how to gauge the size, shape, density and surface features of the plaque or scar within the shaft.

If you have a penis curvature you must have a plaque or scar that is causing it, even if you are at this time unsure how to locate it.

I suggest you get a copy of this important book to learn how to go about finding and defining the scar.   You will use the information of the size, shape, density and surface features of your scar to determine if changes are being made while you undergo Peyronie’s treatment. Without this information you are merely guessing about self-care and this is not a good thing to do.  TRH  

Diet questions
1. is rice milk an acceptable alternate?
2. why no bananas?
thanks

Greetings,

Yes, rice milk is an acceptable alternative drink, and so is almond milk. 

Bananas are to be avoided while doing self-treatment of Peyronies disease for reasons related to ancient oriental principles of yin-yang theory.   As I mentioned in “Peyronie’s Disease Handbook,” if you really want to completely understand why bananas should be avoided you will have to read several acupuncture text books to develop an Eastern insight into this way of looking at things.  The answer is not a simple Western explanation.    TRH  

i have been taking lexapro for about 7 months now – a side effect was diminished sex drive – so, as a result, my partner and I have had sex perhaps twice in those 8 months, ad that was nearly 6 months ago. I have been trying to stimulate myself so we can regain our sex life, modest as it is a this age and, of the last three occasions, i was able to get an strong erection but noticed now my penis is significantly curved upward – needless to say, i feel a bit freakish, and a conflicted between wanting to get aroused but not wanting to see my bent penis. Is it possible to Lexapro had this affect? I am 55 and now feel a “hate” relationship with my penis and not wanting to tell my partner or even have him see it. Basically, i am miserable about this and wanted to know if there is something i can do to help to “straighten out “my boy” and get back to more normal life (also looking to get off the lexapro but my Dr. said not till next year.

Greetings,

There are many side effects of Lexapro.  The most common are:   Constipation; decreased sexual desire or ability; diarrhea; dizziness; drowsiness; dry mouth; headache; increased sweating; light-headedness when you stand or sit up; loss of appetite; nausea; stomach upset; tiredness; trouble sleeping. 

There is no report in the literature of Lexapro causing or leading to development of Peyronie’s disease. 

Before you go off in the wrong direction I advise that you have a medical examination to determine if you have Peyronie’s disease.   If it turns out that you do indeed have Peyronies that your problem started in a more traditional manner of trauma.  A more likely scenario is that while taking Lexapro, or even before starting to take Lexapro,  you sustained injury during sexual activity that resulted in damage to the shaft of the penis.   Please review the information found on this site about Alternative Medicine treatment of Peyronie’s disease.  TRH

If I order Neprinol how much should I lower my present dose of Fibrozym and Nattokinase 1500 dosage to?    I am currently on 7 pills Fibrozym and 5 pills of Nattokinase 1500.  Also do I discontinue fundamental sulfur or continue while on Neprinol?   Do you believe that Neprinol is a better option than Fibrozym and Nattokinase 1500 overall?

Greetings,

Neprinol is a more concentrated form of the systemic enzymes that are found in Fibrozym (serrapeptase) and Nattokinase 1500 (nattokinase).   Neprinol has a higher enzyme activity rating than these two other products.   However, it is not always true that stronger is better or more effective Peyronies treatment.  

My suggestion is that you work with Neprinol to see how you will respond to it compared to Nattokinase and Fibrozym.   You could start taking a total of 4-5 Neprinol daily to determine if changes occur in the size, shape, density or surface features of your scar.   If you determine that there is a positive change in your scar, then you maintain that  same 4-5 Neprinol dosage until your scars disappear.   If at that dosage there are no positive changes in the scar, then you can increase your Neprinol intake until you see reduction of the scar size, shape, density or surface features.  It always comes down to what your tissue requires to make the changes you want.

Many men take all three enzyme products with Neprinol being the primary or lead therapy, but also keep a few Nattokinase 1500 and Fibrozym in their plans as secondary or minor sources of systemic enzymes.     TRH

Where can I get the diet that you recommend for treatment of Peyronie’s disease?

Greetings,

That diet is available and is explained in detail in Chapter 5 of “Peyronie’s Disease Handbook.”   You must remember that PDI recommends a broad base of treatment for PD, using a variety of combined external and internal therapies, with your food intake and how you eat as being a very important part of your overall therapy plan.  This suggests that not rely on any one type of treatment but that you employ them all for best results.    TRH

Hello Doctor,

I was reading about soy free Neprinol AFD on the PDI website.  The statement “soy free” caught my attention.  For some time I have been taking a soy-based energizing protein supplement.  Is there some connection between PD and soy?

About a year ago I began to mix the soy protein with a whey protein in a 1:2 ratio.

Thank you for a very informative web-site.

Sincerely,

Bill

Greetings Bill,

There is no statistical or clinical evidence to suggest that Peyronie’s disease is related to soy intake. That information about Neprinol being soy-free is based on the need of many people to avoid soy in their diet; it is mentioned to let those know who are sensitive to soy that Neprinol can be used for their Peyronie’s treatment.  TRH

My question is really more confusion over the past year of having Peyronie’s disease while using Topical Verapamil cream. My urologist wants me to keep using it and I have lost faith. I would ask your patience, and for you to read my experience because I do not know if the “new” curvature I have now is just due to active Peyronie’s fibrosis or if it was somehow affected by the Verapamil.

If you envision what a moderate erection of a normal penis would look held down by clothing and “worn” to the left of the testicles, when my penis was erect it maintained a similar curvature. I assumed this was my “curse” for being aroused so often every day from the ages of 8 to 18. The curve never caused me pain or any sexual issues, and though would have wished it straight, it was nothing I would have sought treatment for. If not for pain that developed during erection under the left side of my glans, I would never have heard of Peyronie’s Disease.

My Urologist is not a proponent of surgery except in extreme cases, so he prescribed me Topical Verapamil 15% (PD Labs). The confusion I have is that he wants me to keep using is and I think it is a waste of money.

During the first 90 days of use, my penis’ curvature changed drastically. At first I thought that this was due to the Verapamil therapy, but now that it is clear that it was not becoming straight, but rather just curving even more drastically to the left from a different point. The downward curve is gone (a good thing I suppose) but replaced with this almost 90 degree curve to the left about 2.5 inches from the tip.

My Urologist wants me to keep using the Topical Verapamil, but I think that it is a waste of time and money and if it DID effect me, it only facilitated a worsening of the curve. I now have to have “help” to have intercourse with my wife of 27 years! By now we should know where things go and how to put them there, but this has messed that all up! I have minor to no pain, but it is emotionally screwing with me. She thinks it’s no big deal, but I’m sorry. It is to me.

Do you think I should try the enzyme supplement Neprinol?

Greetings,

Sorry to hear of your problem, not only with having Peyronie’s disease but for your experience of worsening while taking Verapamil. 

When I developed Peyronies back in 2002 I also used topical Verapamil.  I used it for six months and my condition slowly worsened,  just as you report.  I assumed then, just as I do now, that the Verapamil was not responsible for the worsening but was totally ineffective to reduce the scar structure and allowed my distortion to increase while taking it. 

I cannot comment on the appropriateness of topical Verapamil treatment in your case.  That is a discussion you should have with the treating doctor who prescribed it for you.   Perhaps his insistence in continuing this drug is more so based on his lack of having anything else he feels he can offer you in good conscience, rather than an overwhelming confidence and belief that it will eventually assist you. One of the articles about Verapamil from the PDI website that might give you helpful information is “Peyronie’s Disease and Verapamil.”

You ask if you should “try” Neprinol as a possible treatment for your Peyronies problem.  

Neprinol is definitely the most popular enzyme we sell in our  Alternative Medicine lineup, but we never – ever –  suggest it should be used alone to treat Peyronie’s disease simply because the problem is too difficult and stubborn.   As good as Neprinol is as a systemic enzyme, from my experience it is almost always necessary to use a few other therapies in addition to Neprinol to create the desired tissue changes.   Neprinol works best used when it is an essential part of a good therapy plan.  When I was actively treating my Peyronie’s disease many years ago I took Neprinol, along with Nattokinase and Fibrozym (but with greater emphasis on Neprinol) as the systemic enzyme part of my larger treatment plan.   I do not think you must do it this way to be successful, I did it just to cover my bases and to keep my tissue as saturated as possible with these enzymes.

I think Neprinol is so important for a successful Peyronie’s treatment plan that I have a large and detailed discussion of this important subject in my book, “Peyronie’s Disease Handbook“.

While Neprinol might be a great systemic enzyme, the men I counsel about their PD who get the best results use more have many other things going for them than just Neprinol.   It is most important to approach your problem from as many different directions at the same time as possible to create synergy.

Some men report just OK results with just one therapy used against PD, but more men report better results when they take multiple therapies.  That is what the whole therapy concept of synergy is all about:  the more you do, the larger your plan, the greater the likelihood of promoting a favorable change in your metabolism that enables you to reduce the Peyronie’s plaque that causes the cured penis that is at the heart of PD.    The idea is not to “treat the scar” as a medical doctor would do, but to “treat the man who has the scar” so that his body can heal what is wrong with it.   This is a basic idea that is fundamental to Alternative Medicine that presents a major shift in thinking for most medically indoctrinated people.   For this reason, as good a single therapy as Neprinol might be,  I do not recommend for  anyone who desires  good Peyronie’s treatment results to use just Neprinol – or just any one product – but several therapies to create the desired synergistic effect. 

There are several special techniques I have worked out over the years for taking Neprinol to increase its potential benefit; it does not work to its maximum benefit if you take it like a vitamin.  After working with thousands of men about their Neprinol usage these special techniques for using systemic enzymes make them more available to you so they will do you the most good.   All of this information is provided when you receive you order from PDI.

PD is a tough and terrible thing to happen to a man.  It takes dedication and persistence to overcome it.   Good luck to you.  Let me know if I can help you in any way.  TRH

Wow, I developed Peyronie disease due to a bend during intercourse. When it happened it felt like blood was filling up the bottom side of my penis. It was 2009 when this happened, its now 2012. I was embarrassed to tell anyone. I believe scar tissue has taken over the bottom side of my penis. It actually feels like a tube running all the way down to my testicles. With me doing research, it seems like a severe case.   Could Scar-X work for my condition?

Greetings, 

Sudden and forceful bending of the penis during intercourse is a very common mechanism to injury that leads to Peyronie’s disease and a curved penis. 

The distribution of scar development you describe is not uncommon; I have many men on the PDI program that describe their scars in a similar pattern and extent.

No where on the PDI website will you find that we suggest anyone treats a problem as stubborn and complicated as Peyronies disease with just one therapy.  Alternative Medicine treatment to be most successful should be broad- based and aggressive.  Using any one therapy,like Scar-X alone, probably would not do much good for you.   Scar-X is a very effective homeopathic formula that is used in Peyronie’s disease treatment to develop a synergistic response in the body to increase the ability to heal and eliminate the PD scar.  I suggest you spend a bit of time reading more information on the PDI website to learn how to put these ideas into action.  TRH     

dear dr herazy,
what can i do to be free of this horrible thing.I have had peyronies for about one year now its completely
ruined my life. can it be cured,how long does it take to go.what can i try.please help…..jim

Greetings Jim,

Your questions are so broad and basic that you make this reply difficult to help you.

You need to spend some time reading the PDI website to learn more what you can do to help yourself. There is not such thing as a Peyronie’s “cure,” although what we do on this website is help men heal their own Peyronies problem to the best extent possible.  

Many men each week report progress to me over their Peyronie’s disease.   Improvement is always work and it is never as fast as anyone would like it to be, but it can be done.  A good place to start is with this link  Start Peyronie’s treatment.  Please ask me what ever specific questions about Peyronies treatment you would like.  I just cannot answer a question so broad and basic as “What can I try?” because it would take hours to answer you.  You must do some digging and investigation on your own, my friend.

Good luck to you.   TRH  

Hello Dr. Herazy,

I am 32 and very recently developed Peyronie’s disease.  I noticed the pain in early November. The pain then resolved itself by late December, around the same time two plaques appeared and a curvature of 5-10 degrees. At the time I developed it, I was under more stress than I can remember experiencing. I’m seeing a urologist next week. So that is my status but I was wondering if I currently masturbate daily do you think that reducing my masturbation by 50-75% would help. Also, in situations such as mine (young, early development, changed lifestyle (much stress now – except for the Peyronies concern)) and with the proper treatment plan the chances of recovery are high? Very very much appreciated….  J

Greetings J,

I have to smile.  Here you think that masturbation might be aggravating your Peyronie’s disease, yet your solution is not to stop masturbating but only to reduce it by 50-75%.   I hope women appreciate this kind of thinking we men have when it comes to sex.

Masturbation, per se, did not cause and cannot aggravate your Peyronie’s disease.   But it could have been the injury and repeated tissue strain that you sustained during masturbation that could have caused or aggravated your Peyronie’s disease.   Do you get the point?   Gentle and easy masturbation that does not injure the tunica albuginea of the penis will not cause Peyronie’s disease.   But the aggressive and sometimes violent masturbation practices and techniques that some men use can injure this deep tissue, causing or aggravating Peyronies disease.  It all depends on how you do it. 

The cause of Peyronie’s disease is complex and not fully understood.   In my opinion your best chance for recovery is found in doing all those things that enable the body to heal as it does in 50% of men who develop PD.  This is what you will find explained in great detail on the PDI website. 

The earlier treatment starts and the more correctly, faithfully and aggressively the treatment is employed, will tend to favor tissue response and eventual recovery.  TRH

Dear Dr. Herazy,

I am 65 years old and have had Peyronie’s disease for about 6mos. It started out gradually when I noticed some difficulty during sex and a small pea-sized nodule on the top of penis.  It has gradually worsened where sex is impossible and erections during the night are terribly bent and painful.  I have been to a uro doc 3x and have tried various rx with little or no success.

I am an active athlete that participates in 3-4 marathons a year and train almost everyday.   The Peyronies disease problem does not interfere with these activities.

Is PDI for me?

Greetings,

I find that many men who appear to be in the peak of health and physical condition, like you,  still develop Peyronie’s disease.   I suppose being in top physical condition does not prevent injury from happening.  Just like athletes still strain and sprain ankles and knees, they also injure the delicate tissue of the penis called the tunica albuginea that leads to PD.   Accidents happen to everyone. 

It is your decision to attempt to assist and boost your Peyronies recovery using the Alternative Medicine methods found on the PDI website. You sound like a good candidate for our concepts, but you should only do it if you are prepared to be faithful and follow the concepts well.  Half-hearted efforts usually result in little change.  If you take that same mindset that enables you run a few marathons annually in your 7th decade, then you should do well.    TRH

My husband, age 56, has been diagnosed by a urologist with Peyronie’s disease. He has had it now for a total of about 6 months.

We live in the Chicago area.   Is there any reason for him to come see you to determine what products he should take or do you simply recommend the same products to all.

Thanks.

Greetings,

I think you have either not spent enough time reading the PDI website, or you misunderstand what you have read.

I do not recommend specific Peyronie’s disease treatment to anyone, and never have.   I do not treat anyone; I do not have a doctor/patient relationship with any of the men I work with from the PDI site.  Men on the PDI website treat and manage their own PD problems, and are encouraged to directly discuss their self-directed PD treatment with their local treating doctor.   I daily suggest to a few dozen men that they should use the most diverse and broad Peyronie’s treatment plan they can faithfully and aggressively follow for a few months.  This happens to be different for each man because their decisions are all different, as well as their eventual dedication and determination are also different.  As each man makes unique decisions for himself, so are their Peyronie’s treatment plans completely unique.    

I do recommend that to be most effective, treatment for Peyronie’s disease must be unique and specific to the man who has the condition.  In this way, I have never worked with one man who has used a Peyronie’s treatment plan that was designed or used like any other man – and I have worked with well over a 1,000 men by now; all treatment is different.

 We currently have four sample PD treatment plans on the PDI website, each one nicely balanced and used by many hundreds of men.  In the description that accompanies each plan you will find that we advise each man can freely add to or subtract from these sample plans or to use them as they are.   Each man must decide for himself how he will best go about his self-directed care. 

Men do not come to me to determine what products they should take.  Men make a basic decision for which plan to start their care based usually on economics and what information they have read about the various therapies.  Regardless of how care starts, care continues and moves in the direction as dictated by how each man’s scar changes or does not change in response to his treatment plan.  this change that he monitors concerns the size, shape, density and surface features of his Peyronie’s plaque or scar.  In this way each individual man works directly with the response of his body to the Peyronies treatment he has started with, and in this way he – not I – determines independently what treatment works best for him.  I do not make any treatment decisions.   When someone asks me a question about treatment I offer in response several ideas and information based on my experience and knowledge.  But it is entirely up to each man to observe his scar response to treatment, and based on this direct information to decide how he wishes to proceed with care.  In this way each man eventually follows his own totally unique plan of care.

I recommend that a man uses the treatment products that are found on the PDI website because I have over 10 years experience working with them and I have confidence in them.   Other products you might use could be of questionable value and ability to help your husband recover.   I cannot offer ideas or information about therapy products that are unknown to me. 

Once a man has a diagnosis of Peyronie’s disease there is no need for me to meet him in person.   With this form of Alternative Medicine treatment there is no need to meet face to face to discuss details or answer questions about PD treatment.  All of that can be easier and more efficiently done over the phone.   I would be pleased to speak with your husband and answer his questions about the PDI method of increasing the ability of the body to heal and repair Peyronie’s disease.   TRH

I had been having problems with pain upon erection and lumps along the shaft of my penis for several months and then I started having a lot more pain.

I went to a urologist who initially told me he couldn’t find anything abnormal but during a subsequent follow-up visit he told me that I have Peyronies Disease and that the lumps were plaque formation and there wasn’t much I could do about it. He advised oral Vitamin E (which I take religiously) and waiting to see if it got better without injections or surgery.

I had never heard of this disease so I have been researching it. I do not have any obvious outward sign like scars or any curvature but I can feel the plaque deposits and have very painful erections.  Sometimes there is pain even without erections. I don’t remember having any specific injury or trauma to my penis during sex but sex definitely makes the pain worse. I am really worried that although there is no curvature now, there will be if I follow the doctor’s “wait and see” plan.

I already feel a “pulling upward” sensation with erections. I would like to know which of your treatment plans would likely be most beneficial to me. The biggest problem is the pain and the lumps that seem to produce this “tugging or pulling” feeling. My first thought is to jump in with both feet into the most aggressive treatment you have but maybe that is not the correct thing to do. I would really appreciate any guidance you can give me.
Greetings,

Thank you for your question.

You must stop doing anything that causes your Peyronie’s disease to be more painful.  Pain indicates that you are again stressing the deep plaque or scar tissue of your Peyronies, and this is harmful and will delay your recovery.  This does not specifically mean stopping sexual intercourse; it only implies you must determine what you  are doing during intercourse, or how you engage in intercourse, that causes physical stress upon the penile tissue and change that aspect of your technique.   This is a huge, diverse and important subject, and for this reason I suggest you should consult a book I wrote, “Peyronie’s Disease and Sex.”    

Taking vitamin E by itself, or taking the wrong kind of vitamin E, no matter how religiously you take it will not help your PD.  You must use the right type of vitamin E, take it at the right time and in combination with other important therapies for it to help your problem.  Please refer to the section in the PDI website about vitamin E that covers this important subject. 

Penile distortion can occur immediately in Peyronie’s disease, but it can also take months or years to develop.  Further,  I have communicated with many men whose PD distortion suddenly worsened after being static for a few years.  For this reason you must not assume your problem will always look the way it looks at this time; they usually worsen over time.    

No one can tell you ahead of time which PD plan will work best for you.   Please read “Do you simply recommend the same treatment products to all Peyronies cases?   You will then understand that all treatment must be unique and driven by specific response of your Peyronie’s plaque or scar.  Lastly, it would appear that you think that the Peyronie’s scar is located on surface of the shaft; it is not.     The PD plaque and scar are terms for the same fibrous material that is found deep within the penis below the skin surface; in the world of PD the scar and plaque mean the same thing.  The scar or plaque are not visible from the exterior since they are internal.

 Let me know if I can help you in any way with eliminating your PD scar with Alternative Medicine.  TRH    

after surgery for peyronies desease how often should you wash the penus and the best way of washing after peyronies surgery and what with?

Greetings,

You really should talk to the doctor who will do your Peyronie’s surgery for the specific answers to this questions.  Your surgeon will help you with this information.  

Is there a reason you believe you need to have Peyronie’s surgery?   Have you tried to help yourself so that you might not need to have penis surgery?    TRH

Hello,

I was wondering about these two products:  Vitamin E Factor 400/400 and the other is  Maxi-Gamma E.

I am probably not understanding this correctly which is why I am emailing, but they seem to both be vitamin e.   Is that correct?   If so why take both? I would be taking too much vitamin e if I take both.   If I am not correct could you explain the difference.

Thank you
Carl

Greetings Carl,

Yes both are vitamin E products.   But, vitamin E is not one thing; vitamin E is actually a family of eight different but related fat-soluble compounds that exist in diverse forms, all widely found in the plant kingdom. There are two basic groups of vitamin E, the tocopherol family and the tocotrienol family; each of these two forms has four subdivisions called alpha, beta, delta and gamma, for a total of eight variations or forms of vitamin E.    Different forms of vitamin E are found in different parts of a plant; the green parts of a plant contain mostly alpha tocopherol and the seed germ and bran contain mostly tocotrienols.

The product Vitamin E Factor 400/400 is very unique in the world of nutrition because it contains a large amount of all eight members of the entire vitamin E family for broad based support of this important vitamin group. 

The product Maxi-Gamma E is also unique because it primarily contains gamma tocopherol, the one member of the vitamin E family that is most responsible for soft tissue healing hence its importance to Peyronie’s disease treatment.   

PDI makes both of these products available – and most men who follow a successful PDI Peyronies treatment plan will use both products  typically taking one of these in the AM and the other in the PM.

Why do you think that taking both would be too much?   Overdosing with vitamin E occurs at a relatively low dose only when synthetic vitamin E is taken.  PDI only supplies natural forms of vitamin E that are organic.  Please see this article   Peyronie’s Disease Treatment and Vitamin E for a discussion about the silly vitamin E scare that is going around simply because people do not understand the story behind vitamin E.  You will understand the background of how poor research and bias maligns even a naturally occurring vitamin that is essential for health.

Unfortunately most vitamin E supplements contain only alpha-tocopherol. This information should make it all the more obvious why a Peyronies disease victim needs to carefully choose supplements that contain the complete vitamin E family of tocopherols plus tocotrienols and any that are  especially rich in gamma-tocopherol. Like all families, each member has certain strengths and abilities, requiring a variety of workers to support the necessary tissue changes needed to improve the health and resistance of tissue damaged in PD. Here is a list of the eight forms of vitamin E:

Tocopherol group

Alpha-tocopherol
Beta-tocopherol
Gamma-tocopherol
Delta-tocopherol

Tocotrienol group

Alpha-tocotrienol
Beta-tocotrienol
Gamma-tocotrienol
Delta-tocotrienol

Each of the two forms has its own area of use or activity in the body. The tocopherol forms function as strong antioxidants, with the alpha form being the most active of the four subdivisions. Vitamin E, like all antioxidants, protect at the cellular level against the effects of potentially damaging by-products of metabolism, called free radicals. A free radical is a molecule that has been involved in a chemical process in the body, and in so doing becomes unstable when it loses an electron. Free radicals can cause cell damage by attracting electrons from stable molecules in other areas in the body, thus making additional cells also unstable.

Unless they are connected to an antioxidant, highly unstable free radicals attack the polyunsaturated fatty acids of cell membranes in a chain reaction. This process of losing and gaining electrons might contribute to the development of heart disease, cancer; Alzheimer’s disease, arthritis, premature aging and cataracts and even excess scar formation.

Peyronie’s and vitamin E connection

The tocotrienol form of vitamin E has shown superior action in maintaining arterial health because of its ability to reduce plaque and fibrous tissue infiltration in damaged arterial walls. This same ability is suspected to result in reduction of scar and fibrous tissue buildup in other parts of the body.

Vitamin E has 75% worldwide approval as a first-line treatment of Peyronie’s disease, yet its effectiveness has not been proven to scientific standards. It is the most popular of the alternative treatments used. Vitamin E is perhaps the most researched and tested of the alternative methods for treatment of PD, and yet it has not been researched or tested very much. It has been heavily researched and tested for other health conditions that have the same or similar scar and fibrous tissue formation, and it has proven its effectiveness. Use of vitamin E is based not only on the positive results it gets with Peyronie’s disease, but also the positive results scored against other health conditions similar to it.

Maybe your family doctor or local urologist doesn’t recommend using vitamin E for PD, but you can now see there is a lot of science backing up this idea, and there are thousands of doctors from around the world who use it successfully. You are now aware of some of the reasons it is used as a first-line of treatment against Peyronie’s disease. If you were going to use only one therapy to improve the health of your tissue and increase your chance of repairing some of the damage of PD, vitamin E should be considered as that one thing.

Using vitamin E – and therefore vitamin C – is the perhaps the most commonly recommended conservative method to assist the healing of the PD scar in traditional medical practice, as well as alternative medical practice.

I hope this information helps you understand the role of vitamin E in Peyronie’s disease treatment.  TRH

I have 0 pain, 0 curve in erection and no hourglass look in erection.

However I am 18, and have had ed for 4 years. For as long as I can remember, on the occasion, My flaccid penis has a bit of the hourglass look. Also when it is night time, and I am extremely relaxed, and my flaccid becomes bigger, and almost a semi erect, it occasionally curves to the right which i just started noticing about 6 months ago. Also, after I urinate, occasionally I see my penis begin to curve right.

Again no pain, no bumps, no hourglass or curve in erection

I only see hourglass/curve in flaccid/semi erect.  Is this Peyronies disease?  If so will it get worse?  Can I send pictures to you?

Greetings,

Pictures would be of little help to reach a conclusion.

No one can say with any level of certainty based on the information you have provided whether your condition is Peyronie’s disease or not.  These things are not diagnosed so casually or easily.   To know for sure what is happening, you must see a urologist and be examined for a formal diagnosis.

Having said that, it is my absolute guess that you do not have Peyronies disease for the following reasons you cite:
1.  Lifelong penile distortion, not recent onset
2.  Distortion when semi-erect or flaccid, not eerect
3.  Occasional distortion, not constant or very frequent
4. No mention of trauma
5. No mention of familial PD or DC problem
6. No penile curvature
7. No pain
8. No mass or lump, apparently; these can be missed even with PD, but in many cases the scar or plaque is easily found.

Please go to a good urologist and get to the bottom of your problem.   TRH

Dear Dr. Herazy,
I have been diagnosed with Peyronie’s disease, but I also have some other health issues that I am being treated for. I want to know if any of the substances used in your PD treatment will interact negatively with my current prescription medications. I am taking 1 Levothriod tab 88mcg on an empty stomach, for my thyroid; 1 Sulfamethoxazole/Trimethopr at bedtime ( I have an Atonic bladder and must self catheterize every time I urinate); I also take 1 Acyclovir tab 400mg twice daily for herpes prevention. I think my herpes outbreaks contributed to the development of my PD. I want to start treating my PD because, as per your website, my Urologist tried me on Verapomil ointment, but it irritated my skin, and he has’t been fortcoming with any other treatment ( wait and see). I also have BHP, and he is watching my PSA levels, (I have had three biopsys, all negative. Thank you for any information on my question.

Sincerely,
Lou

Greetings Lou,

Sorry to hear of your current situation.

The best answer I can give you is in two parts. First, no one in over ten years of this work has reported a drug interaction occurrence as a result of taking any natural Peyronies treatment product.  These are all naturally occurring substances, for the most part nutritional in nature.  There would be little reason to think that any medication would have an adverse reaction with a nutritional product.  Second, I suggest you present the list of therapies that you decide to take as an Alternative Medicine treatment for Peyronie’s disease and present it to the medical doctor who prescribed these drugs to you.   He can offer his opinion about the appropriateness of combining these two different forms of treatment.    

Hi,
I was a customer a few years ago and cured mostly my Peyronies scar through your plans. My penis is mostly back to its normal form now and painless, and that is good. My question today is concerning a topical scar, not a scar on my penis. I have a long rubbery keloid scar on my forearm which keeps slowly snaking it’s way down my arm year by year. And before trying to have it frozen off I’d like to try your enzymes and CP Serum and such.

I would like to know which enzymes of yours to try first? The Quercetin/Bromelain combo or just the new 5000 Bromelain? And the Copper solution with DMSO? Also, have you heard any research on Lugol’s solution and iodine concerning topical scars?

Thank you for your time.

Greetings, 

Glad to hear your feedback on your successful results following the PDI concepts of Peyronie’s treatment.  You really should write back to this same Q/A section and provide some insight and experience you gained while successfully treating your Peyronie’s disease.

I have had many men tell me over the years that they have used a very similar scar treatment plan that follows their PD plan.  I do not have much feedback from these men about scar treatment but that idea makes sense to me.  Let me know what happens for you.  TRH